Drug Intermediate
Drug Iintermediate
Drug intermediates are used as raw materials for the production of bulk drugs, or they can refer to a material produced during synthesis of an API that must undergo further molecular change or processing before it becomes an API. Drug intermediates are hygienically formulated using high grade raw materials and they are used in the pharmaceutical and cosmetic industry[1][2].
References:
- [1]. Ma HC, et al. Homochiral Covalent Organic Framework for Catalytic Asymmetric Synthesis of a Drug Intermediate. J Am Chem Soc. 2020 Jul 22;142(29):12574-12578. [Content Brief]
- [2]. Ramachary D B, et al. Development of pharmaceutical drugs, drug intermediates and ingredients by using direct organo‐click reactions[J]. 2008.
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Drug Intermediate 관련 제품 (4520)
관련 제품 (4520)
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Me-diazirine-cooh
0 ImagesSynonyms: 3-(3-Methyl-3H-diazirin-3-yl)propanoic acidMe-diazirine-cooh (3-(3-Methyl-3H-diazirin-3-yl) propanoic acid) is a molecular building block containing an aliphatic diazirine ring. Me-diazirine-cooh undergoes orthogonal coupling in solid-phase peptide synthesis to introduce the Diazirine group into collagen-mimetic peptides. Me-diazirine-cooh is used to construct the photoaffinity probe P1.
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4-Chlorobenzoic acid
0 Images4-Chlorobenzoic acid is a halogenated aromatic compound that can be used as an industrial chemical and an intermediate in drug synthesis. 4-Chlorobenzoic acid is a persistent organic micropollutant and can be biodegraded through a direct dehalogenation pathway.
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1-Boc-3-benzyl-3-piperidinecarboxylic acid
0 Images1-Boc-3-benzyl-3-piperidinecarboxylic acid is a drug intermediate for synthesis of various active compounds.
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Bis(2-cyanoethyl) diisopropylphosphoramidite
0 ImagesCat. No.: HY-24126CAS No.: 102690-88-0Bis(2-cyanoethyl) diisopropylphosphoramidite is a phosphorite monomer that can be used in the synthesis of oligonucleotides.
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1,2,6,7-Tetrahydroindeno[5,4-b]furan-8-one
![1,2,6,7-Tetrahydroindeno[5,4-b]furan-8-one](https://file.medchemexpress.com/product_pic/hy-32233.gif "Click to View 1,2,6,7-Tetrahydroindeno[5,4-b]furan-8-one Product Detail")
0 Images1,2,6,7-Tetrahydroindeno[5,4-b]furan-8-one is a drug intermediate for synthesis of various active compounds.
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6-Hydroxynicotinic acid
0 Images6-Hydroxynicotinic acid is an intermediate in the oxidation of Nicotinic acid (HY-B0143) by Pseudomonas fluorescens and metabolite. 6-Hydroxynicotinic acid can be isolated from root exudates of Cucumis melo. 6-Hydroxynicotinic acid disrupts the Auxin signaling pathway. 6-Hydroxynicotinic acid inhibits haustoria precursor formation in Phlipanche aegyptiaca.
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2-Naphthaldehyde
0 Images2-Naphthaldehyde belongs to naphthalene-based bis-aromatic aldehyde compounds. 2-Naphthaldehyde scavenges DPPH and ABTS+ free radicals, and exerts reductive effects by donating hydrogen atoms to interrupt free radical chain reactions. 2-Naphthaldehyde inhibits the growth and proliferation of colon cancer cells. 2-Naphthaldehyde serves as a substrate for NAD+-dependent salicylaldehyde dehydrogenase from Pseudomonas strain C6 and is catalytically oxidized. 2-Naphthaldehyde acts as a precursor material for the chemical synthesis of antioxidant Schiff bases.
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3-Benzyl-6-bromo-2-methoxyquinoline
0 Images3-Benzyl-6-bromo-2-methoxyquinoline is a drug intermediate for synthesis of various active compounds.
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N-Chlorosuccinimide
0 ImagesN-Chlorosuccinimide (Succinchlorimide) is an oxidizing, hydrolyzable biochemical reagent with bactericidal and amoebicidal activities. N-Chlorosuccinimide can either form N-chloramines via concerted transfer of Cl+ or hydrolyze in aqueous solution to produce hypochlorous acid/hypochlorite. N-Chlorosuccinimide is effective in killing Shigella dysenteriae, Escherichia typhi and cysts of Entamoeba histolytica. N-Chlorosuccinimide can be formulated into fast-dispersing, fully soluble water purification tablets. N-Chlorosuccinimide is used in studies related to bacterial infections and parasitic infections.
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cis-Benzyl 3-hydroxycyclobutylcarbamate
0 Imagescis-Benzyl 3-hydroxycyclobutylcarbamate is a drug intermediate for synthesis of various active compounds.
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N-Methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine
![N-Methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine](https://file.medchemexpress.com/product_pic/hy-40352.gif "Click to View N-Methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine Product Detail")
0 ImagesN-Methyl-N-((3R,4R)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine is a drug intermediate for synthesis of various active compounds.
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2-(((3aR,4S,6R,6aS)-6-((5-Amino-6-chloro-2-(propylthio)pyrimidin-4-yl)amino)-2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-yl)oxy)ethanol
![2-(((3aR,4S,6R,6aS)-6-((5-Amino-6-chloro-2-(propylthio)pyrimidin-4-yl)amino)-2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-yl)oxy)ethanol](https://file.medchemexpress.com/product_pic/hy-78055.gif "Click to View 2-(((3aR,4S,6R,6aS)-6-((5-Amino-6-chloro-2-(propylthio)pyrimidin-4-yl)amino)-2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-yl)oxy)ethanol Product Detail")
0 Images2-(((3aR,4S,6R,6aS)-6-((5-Amino-6-chloro-2-(propylthio)pyrimidin-4-yl)amino)-2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-yl)oxy)ethanol is a drug intermediate for synthesis of various active compounds.
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tert-Butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate
0 Imagestert-Butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate is a drug intermediate for synthesis of various active compounds.
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16-Hydroxyhexadecanoic acid
0 ImagesSynonyms: Juniperic acid16-Hydroxyhexadecanoic acid (Juniperic acid) is one of the main monomers of cutin in Vicia faba flower petals. 16-Hydroxyhexadecanoic acid can be used as an internal standard for the measurement of hydroxy and hydroperoxy fatty acids in plasma.
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5,6-Dimethyl-1H-benzo[d]imidazole
![5,6-Dimethyl-1H-benzo[d]imidazole](https://file.medchemexpress.com/product_pic/hy-w017511.gif "Click to View 5,6-Dimethyl-1H-benzo[d]imidazole Product Detail")
0 Images5,6-Dimethyl-1H-benzo[d]imidazole is an endogenous metabolite. 5,6-Dimethyl-1H-benzo[d]imidazole is also a benzimidazole derivative and can be used in the synthesis of other active compounds.
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GDP-D-mannose disodium
0 ImagesGDP-D-mannose disodium consists of GDP-α-D-mannose (HY-N7389B) and GDP-β-D-mannose. GDP-α-D-mannose serves as a donor substrate for mannosyltransferases and acts as a precursor of GDP-β-L-fucose. GDP-α-D-mannose exerts competitive inhibition on GTP (with a Ki value of 14.7 μM) and non-competitive inhibition on mannose-1-P (with a Ki value of 115 μM). GDP-D-mannose disodium is metabolized to GDP-L-fucose (HY-134433) via GMDS (Gmd) and TSTA3 (WcaG).
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Hercynine
0 ImagesSynonyms: Histidine-betaineHercynine (Histidine-betaine) is an intermediate (precursor) and a redox metabolite of Ergothioneine (HY-N1914), which is found in the fine leaf algae, Schizosaccharomyces cerevisiae and honey bees. Hercynine has no effect on scavenging •OH radicals.
